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With no further treatment, the 1996 ten-month follow-up data (n=92) from a high pollen period in Oregon, Washington and hair Idaho together showed a greater reduction in the active hosting add ons group (n=43) than the placebo group (n=49) on the primary endpoint, defined as a combination of symptom and rescue medication scores.8 patients gave blood serum ons samples prior to the treatment in 1995 and one year later in 1996. they were immunoassayed for specific hair ige antibodies using a chemi-luminescent technique. statistician bradley rosebrook ran t-tests comparing add average baseline ige levels to one-year. for the seasonal allergens reported, ons and hair the active group (n=27) had on average a greater reduction in ige than the placebo group (n=34) for 13 out of 16 allergens.8

studies add indicate that ingested oral cyanocobalamin tablets are ineffective in the treatment of allergic disease, perhaps because once ingested, they are directly metabolized in the liver. when b12 is delivered via injection or lozenge it passes throughout the bloodstream ons before hair arriving at add the liver. it is during this first pass in its native form that it is believed to exert its therapeutic effect. clinical research: "the world health organization (who) recognizes allergic ons rhinitis (hay fever), sinusitis, asthma,...conjunctivitis, urticaria, eczema, dermatitis (contact and atopic)...allergic and migraine headache...as diseases in which ige-mediated allergy may be involved."1 in 1988, asthma and allergic rhinitis subjects were treated with b12. total ige, specific hair ige and pulmonary lung functions were taken at days 45, 150 and 180 from baseline. eight add of the 9 subjects had reduced ige. 2 in 1989 open label studies at two sites in riverside ons county, ca in 1989. sixteen of the 17 subjects had lowered ige levels from day 0 to day 30.3